S. Roselló, E. Llorens, G. Camañes, M. Hurtado
This paper introduces IntGenSim (Interactive Genetic Simulator), an innovative educational tool. This software allows users to effortlessly construct virtual populations of diploid organisms by defining each individual's genome via an intuitive graphical representation. It also enables the definition of genetic traits (both qualitative and quantitative) controlled by one or several genes, which can then be evaluated within the created populations. IntGenSim calculates phenotypes by first assessing the alleles present in each genotype for a given trait's genes and then deriving the corresponding phenotypic expression. Furthermore, selection based on phenotypic values can be conducted after graphically choosing specific selection criteria. Additionally, the software supports the creation of new populations from existing ones. Through the simulation of biological processes like gamete generation and zygote formation, the software enables interactive exploration of the genetics of evolutionary or breeding processes. IntGenSim enables students to concurrently visualize both the genotype and the phenotype for a specific trait, providing a valuable insight given that only phenotypes are directly observable in natural systems. This feature significantly helps students consistently learn genetics concepts and applying them to study evolutionary processes and breeding programs. This work describes the main components and functionalities of the IntGenSim tool and showcases its educational applications in several Genetics courses offered within the Agricultural Engineering and Biochemical and Molecular Biology degrees at the Universitat Jaume I in Castellón.
Keywords: Virtual Learning Environment (VLE), Simulation Software, Graphical Genotypes, Dinamic Phenotipe Filtering, Excel VBA programming.