The integration of artificial intelligence (AI) into educational systems is gaining traction globally, and this trend is also emerging in Ghana. The potential and challenges of AI usage in Ghanaian education have motivated this study. Specifically, the study sought to examine the general perceptions of university teachers in Ghana on the use of AI in education and identify the challenges and barriers they face in implementing AI. The study adopted a quantitative data-gathering method. Questionnaires were administered to five hundred (915) university teachers, and 833 responses were received. The analysis revealed that most university teachers see AI as a valuable educational tool that can enhance learning and teaching processes. However, significant challenges were identified, including a lack of infrastructure, insufficient training on AI applications, and resistance to change. The consequences of these findings from the viewpoints of university teachers suggest that there is a need for substantial investment in AI infrastructure, comprehensive training programs for teachers, initiatives to overcome resistance to the adoption of AI in education, and policies aimed at equitable access to AI tools in education.

Keywords: Artificial Intelligence (AI), Technology, Ghanaian education, University Teachers, educational Technology.