Gamification, defined as the integration of game-like elements into non-gaming contexts, has gained attraction as a convenient strategy to enhance learning experiences across different disciplines, particularly in science education. In particular, Medicinal Chemistry, a core subject in Pharmacy Grade, poses challenges for students due to its complex theoretical and practical components. This paper proposes a gamified intervention for a third-year Medicinal Chemistry course at the University of Seville, aimed at transforming traditional learning into an interactive and engaging experience. The design leverages constructivist and problem-based learning principles to immerse students in a fictional narrative, "The Cure Quest," where they undertake missions that simulate real-world drug development processes. Each mission, progressively complex, focuses on core concepts such as molecular identification, reaction mechanisms, pharmacokinetics, and toxicology. Anticipated outcomes include enhanced knowledge retention, critical thinking, and student motivation, alongside practical skills applicable to professional contexts. By integrating digital tools and immediate feedback mechanisms, the intervention seeks to bridge theoretical knowledge and its real-world application. This proposal illustrates the potential of gamification to revolutionize science education, offering insights for broader implementation across related disciplines.

Keywords: Gamification, Medicinal Chemistry, Constructivist Learning, Problem-Based Learning, Science Education, Engagement, Drug Development Simulation.